yep, lyme is a nasty one. my understanding is that part of the issue is that it frequently does not get diagnosed until it is too late to catch it fully. i know 3 people with it, and each of them was not diagnosed for at least a year after symptoms first started showing. they will likely have some level of symptoms for the rest of their lives, so they have been told.
it is for that reason that after i had been bitten by a tick in the southeast a couple years ago, as soon as i saw symptoms - my visible symptoms were for rocky mountain spotted fever, not lyme - i went to urgent care and got some intense antibiotics. i had a worse reaction to the pills (i had not taken scrip meds for probably 30 years) than i had to the tick bite, and i likely got it in time. that is one situation where time is definitely of the essence.
apparently, there are 5 common to humans tick-borne diseases (with lyme and rocky mountain spotted fever being the most well known), and most often if someone gets one of them, they have one or more of the others as well. very few ticks apparently carry only one of those pathogens. edit: the medical industry treats all 5 with the same drugs, best i can tell. a more natural approach might be a bit more specific/selective.
yet another reason why i love living at high altitude in a dry and fairly inhospitable environment. :-)